English Version of Clinical Practice Guidelines for the Management of Atopic Dermatitis 2021

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  • Hidehisa Saeki
    Department of Dermatology Nippon Medical School Tokyo Japan
  • Yukihiro Ohya
    Allergy Center, National Center for Child Health and Development Tokyo Japan
  • Junichi Furuta
    Medical Informatics and Management, Faculty of Medicine University of Tsukuba Tsukuba Japan
  • Hirokazu Arakawa
    Kitakanto Allergy Research Institute Kibounoie Hospital Midori Japan
  • Susumu Ichiyama
    Department of Dermatology Nippon Medical School Tokyo Japan
  • Toshio Katsunuma
    Department of Pediatrics The Jikei University Daisan Hospital Tokyo Japan
  • Norito Katoh
    Department of Dermatology Kyoto Prefectural University of Medicine Graduate School of Medical Science Kyoto Japan
  • Akio Tanaka
    Department of Dermatology, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Yuichiro Tsunemi
    Department of Dermatology Saitama Medical University Saitama Japan
  • Takeshi Nakahara
    Department of Dermatology, Graduate School of Medical Sciences Kyushu University Fukuoka Japan
  • Mizuho Nagao
    Allergy Center, National Hospital Organization Mie National Hospital Tsu Japan
  • Masami Narita
    Department of Pediatrics, Faculty of Medicine Kyorin University Tokyo Japan
  • Michihiro Hide
    Department of Dermatology, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Takao Fujisawa
    Allergy Center, National Hospital Organization Mie National Hospital Tsu Japan
  • Masaki Futamura
    Division of Pediatrics National Hospital Organization Nagoya Medical Center Nagoya Japan
  • Koji Masuda
    Department of Dermatology Kyoto Prefectural University of Medicine Graduate School of Medical Science Kyoto Japan
  • Tomoyo Matsubara
    Department of Pediatrics Dokkyo Medical University Saitama Medical Center Saitama Japan
  • Hiroyuki Murota
    Department of Dermatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Kiwako Yamamoto‐Hanada
    Allergy Center, National Center for Child Health and Development Tokyo Japan

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<jats:title>Abstract</jats:title><jats:p>This is the English version of the Clinical Practice Guidelines for the Management of Atopic Dermatitis 2021. Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion. In Japan, from the perspective of evidence‐based medicine, the current strategies for the treatment of AD consist of three primary measures: (i) use of topical corticosteroids, tacrolimus ointment, and delgocitinib ointment as the main treatment of the inflammation; (ii) topical application of emollients to treat the cutaneous barrier dysfunction; and (iii) avoidance of apparent exacerbating factors, psychological counseling, and advice about daily life. In the present revised guidelines, descriptions of three new drugs, namely, dupilumab, delgocitinib, and baricitinib, have been added. The guidelines present recommendations to review clinical research articles, evaluate the balance between the advantages and disadvantages of medical activities, and optimize medical activity‐related patient outcomes with respect to several important points requiring decision‐making in clinical practice.</jats:p>

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