Guidelines for the treatment of childhood-onset Graves’ disease in Japan, 2016
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- Minamitani Kanshi
- Department of Pediatrics, Teikyo University Chiba Medical Center, Chiba, Japan
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- Sato Hirokazu
- Sunrise Children’s Clinic, Chiba, Japan
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- Ohye Hidemi
- Department of Internal Medicine, Ito Hospital, Tokyo, Japan
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- Harada Shohei
- Division of Neonatal Screening, National Center for Child Health and Development, Tokyo, Japan
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- Arisaka Osamu
- Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan.
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<p>Purpose behind developing these guidelines: Over one decade ago, the “Guidelines for the Treatment of Graves’ Disease with Antithyroid Drug, 2006” (Japan Thyroid Association (JTA)) were published as the standard drug therapy protocol for Graves’ disease. The “Guidelines for the Treatment of Childhood-Onset Graves’ Disease with Antithyroid Drug in Japan, 2008” were published to provide guidance on the treatment of pediatric patients. Based on new evidence, a revised version of the “Guidelines for the Treatment of Graves’ Disease with Antithyroid Drug, 2006” (JTA) was published in 2011, combined with the “Handbook of Radioiodine Therapy for Graves’ Disease 2007” (JTA). Subsequently, newer findings on pediatric Graves’ disease have been reported. Propylthiouracil (PTU)-induced serious hepatopathy is an important problem in pediatric patients. The American Thyroid Association’s guidelines suggest that, in principle, physicians must not administer PTU to children. On the other hand, the “Guidelines for the Treatment of Graves’ Disease with Antithyroid Drug, 2011” (JTA) state that radioiodine therapy is no longer considered a “fundamental contraindication” in children. Therefore, the “Guidelines for the Treatment of Childhood-Onset Graves’ Disease with Antithyroid Drug in Japan, 2008” required revision.</p>
収録刊行物
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- Clinical Pediatric Endocrinology
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Clinical Pediatric Endocrinology 26 (2), 29-62, 2017
日本小児内分泌学会
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詳細情報
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- CRID
- 1390282679461384576
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- NII論文ID
- 130005606259
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- ISSN
- 13477358
- 09185739
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- 使用不可